Avaliação dos extratos das cepas de fungos Amazônicos (Trametes lactinea e Hexagonia glabra) e de seus consórcios frente às Bactérias Escherichia coli, Staphylococcus aureus e Proteus vulgaris

Abstract

The Amazon region is home to many life forms with great biotechnological potential, and among these are the fungi that produce metabolites of industrial interest such as antibiotics and enzymes that represent a large global market. Many of antibiotics used to treat diseases were extracted from fungi, such as penicillin, substance produced by the fungus Penicillium notatum. , Therefore it is known among these antimicrobial activity of Trametes lactineae and Hexagonia glabra and its possible synergistic interaction, allowing viable alternatives in the search for new antimicrobial substances. A collection was held in the city of Tefé-AM. The fruiting bodies were dehydrated at 35ºC for 24 hours was used 0.4 mg of the crude extract was diluted in 20μl of DMSO subsequently added 1.96 ml of water destilada.Os microorganisms were cultivated nutrient medium (NA), for 24h at 37ºC oven will. Strains of Escherichia coli, Staphylococcus aureus and Proteus vulgaris were seeded in Petri dishes containing Mueller Hinton. The experiment was performed in triplicate, used the disc diffusion technique of ± 0.5 cm in use 4 discs per plate. Generally all microorganisms were sensitive to metabolites produced by fungi Trametes lactinea and hexagonia glabra, is worth mentioning that there was a synergistic interaction between the extracts evaluated, that this was potentiated by more than 100% activity against the microorganism Proteus vulgaris. Despite the favorable results of this research showed some gaps to be filled in the future to better understand the possible formulation of a final product.