Carcinoma espinocelular relacionado ao hábito de mascar tabaco relato de caso clínico

Abstract

Or squamous cell carcinoma has its multifactorial etiology, resulting from the interaction of intrinsic and extrinsic carcinogenic factors. The main risk factors for its development are: tobacco, alcohol, HPV virus, malnutrition, heredity, solar radiation, trauma. The objective of this work was to describe a clinical case of squamous cell carcinoma related to the habit of chewing tobacco in an elderly patient. Predisposing factors are reported, as well as the review of the literature regarding squamous cell carcinoma. Individual male, chewed tobacco for thirty years, who sought the Dental Polyclinic of the State University of Amazonas (UEA), whit wound complaint in the mouth is about 5 months. The intraoral clinical examination revealed ulcerated lesion with dark spots about 1 cm in peripheral its largest diameter, located at bottom of vestibular Groove in the region right retromolar trigone. Before the data from anamnesis and clinical characteristics were raised diagnostic hypotheses of squamous cell carcinoma and Verrucous carcinoma. Incisional biopsy fragments were sent for pathology in the oral pathology laboratory of the UEA. Histological sections revealed the buccal mucosa lined with stratified epithelium keratinized hyperplastic pavimentoso showing the basal layer, layers increased, parabasais, hipercromatismo, pleomorphism any atypical mitosis, and Dyskeratosis pearls corneas. Underlying connective tissue appears disorganized by islets and neoplastic epithelium sheets, showing perivascular invasion, focal and moderate hemosiderosis mononuclear inflammatory infiltrate Lympho-histiocytic, provisions of discussion the region. The histopathological diagnosis was of well differentiated squamous cell carcinoma. The patient was referred to the Oncology Center Foundation of the State of Amazonas (FCECON) for evaluation and treatment. This report shows the relationship of tobacco consumption for a long period of time and the development of squamous cell carcinoma, which was confirmed by Histopathological examination