Psoríase pustulosa desencadeada pelo uso de corticoide sistêmico

Abstract

Psoriasis is a chronic inflammatory disease of multifactorial etiology, with participation of genetic, autoimmune and environmental factors and varied clinical presentations. The annular pustular psoriasis is a rare subtype of pustular psoriasis with erythematous scaly lesions or annular circinate, centrifugal growth and formation of peripheral sterile pustules. It can occur as an isolated clinical form without prior evidence of psoriasis, or be triggered by aggravating factors in patients previously diagnosed with psoriasis. In this paper, we report a case of a female patient, 41, with psoriasis for 24 years, who presented sudden appearance of erythematous annular and circinate lesions with raised edges topped with pustules, compromising trunk and root of the members, three weeks later the use of injectable steroid in unit responsiveness. It was initially treated with acitretin 0.75 mg / kg / day, with little clinical improvement, and then started treatment with immunobiological medication, progressing to clinical remission after 60 days of starting treatment. Remains without skin lesions of psoriasis to date, 24 months after introduction of this treatment. Keywords: Pustular psoriasis, systemic corticosteroids, treatment.